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Omeprazole

 

Generic Name: omeprazole (oh MEP ra zol)
Brand Names: FIRST Omeprazole, PriLOSEC, PriLOSEC OTC, Zegerid (Original Formulation)

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What is omeprazole?

Omeprazole (Prilosec, Zegerid) belongs to group of drugs called proton pump inhibitors. It decreases the amount of acid produced in the stomach.
Omeprazole is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions caused by excess stomach acid. It is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).
Omeprazole may also be given together with antibiotics to treat gastric ulcer caused by infection with helicobacter pylori (H. pylori).
Omeprazole is not for immediate relief of heartburn symptoms.

Important information

Omeprazole is not for immediate relief of heartburn symptoms.
Heartburn is often confused with the first symptoms of a heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, and a general ill feeling.
You should not take this medication if you are allergic to omeprazole or to any other benzimidazole medication such as albendazole or mebendazole.

Slideshow

GERD and Heartburn: What Is GERD?

Ask a doctor or pharmacist if it is safe for you to take omeprazole if you have liver disease or heart disease, or low levels of magnesium in your blood.
Some conditions are treated with a combination of omeprazole and antibiotics. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice.
Take omeprazole for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared.
Prilosec OTC (over-the-counter) should be taken for no longer than 14 days in a row. Allow at least 4 months to pass before you start another 14-day treatment.

Before taking this medicine

You should not use this medicine if you are allergic to omeprazole or to any benzimidazole medicine such as albendazole or mebendazole.
Heartburn is often confused with the first symptoms of a heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, and a general ill feeling.
Ask a doctor or pharmacist if it is safe for you to use omeprazole if you have other medical conditions, especially:

• liver disease;
  
• low levels of magnesium in your blood; or
  
• osteoporosis or low bone mineral density (osteopenia).
  

Do not use over-the-counter omeprazole (Prilosec OTC) without the advice of a doctor if you have:

• trouble or pain with swallowing;
  
• bloody or black stools, vomit that looks like blood or coffee grounds;
  
• heartburn that has lasted for over 3 months;
  
• frequent chest pain, heartburn with wheezing;
  
• unexplained weight loss; or
  
• nausea or vomiting, stomach pain.
  

Taking a proton pump inhibitor such as omeprazole may increase your risk of bone fracture in the hip, wrist, or spine. This effect has occurred mostly in people who have taken the medication long term or at high doses, and in those who are age 50 and older. It is not clear whether omeprazole is the actual cause of an increased risk of fracture.